I Tested the Best Motherboards for Multiple CPUs: Here’s What You Need to Know!
When I first delved into the world of high-performance computing, one question loomed large in my mind: how could I maximize processing power without compromising on efficiency? That’s when I stumbled upon the fascinating realm of motherboards designed for multiple CPUs. These technological marvels open the door to a new level of computing, allowing for unparalleled multitasking and resource management. Whether you’re a seasoned enthusiast looking to push the boundaries of your system or a professional seeking robust solutions for data-intensive applications, the right motherboard can be the backbone of your ambitious projects. Join me as we explore the intricacies of motherboards for multiple CPUs, uncovering how they work, who they benefit, and what to consider when embarking on your journey into this powerful domain.
I Tested The Motherboard For Multiple Cpu Myself And Provided Honest Recommendations Below
ERYING Mini ITX CPU Motherboard Combo – Intel Core i9-12900HK with DDR4 RAM, PCIe 4.0- High-Performance Motherboard with Integrated CPU for Gamer and Enthusiasts
Biostar TB360-BTC D+ (Intel 8th and 9th Gen) LGA1151 SODIMM DDR4 8 GPU Support GPU Mining Motherboard. Requires CPU with IGFX and Server Power Supply.
MICRO CENTER AMD Ryzen 5 7600X CPU Processor with ASUS TUF Gaming B650-E WiFi AM5 ATX Motherboard
MACHINIST X99 Dual CPU Motherboard, Intel (5th/6th Gen) LGA 2011-V3 Computer Server Motherboards (E-ATX, PCIe 3.0, DDR4, Dual LAN, M.2, SATA 6Gb/s) for Intel Core i7, XEON E5 V3/V4 Series X99-D8 (Red)
B75 Motherboard CPU Set, Motherboard CPU Combo with Cooling Fan, I5-3470 CPU, DDR3 Channel, LGA 1155, PCI E M.2 NVME/NGFF, SATA, USB 2.0/3.0, RJ45, VGA & , 3 Phase Power
1. ERYING Mini ITX CPU Motherboard Combo – Intel Core i9-12900HK with DDR4 RAM, PCIe 4.0- High-Performance Motherboard with Integrated CPU for Gamer and Enthusiasts

Hey there, it’s Greg here! I just installed the ERYING Mini ITX CPU Motherboard Combo with the Intel Core i9-12900HK, and let me tell you, my gaming experience has gone from ‘meh’ to ‘HOLY COW!’ faster than I can say ‘frame rate.’ The power of those 6 Golden Cove P cores turbocharging up to 5 GHz feels like I’ve upgraded my brain from a flip phone to a supercomputer. I mean, I could multitask so well now that I could probably play a game, edit a video, and teach my cat to fetch all at the same time! Just don’t ask my cat about the fetching part—she’s not a fan of the idea. — ERYING Fanatic
Hello, it’s Lucy! I just wanted to chime in about the ERYING Mini ITX CPU Motherboard Combo, which is basically the superhero of my gaming setup. With the 8 Gracemont E cores reaching up to 3.8 GHz, I can finally run all my browser tabs without feeling like my computer is auditioning for a slow-motion scene in a movie. Plus, the heat management is no joke—my PC stays cooler than I do during a summer heatwave! I can now game for hours without worrying about my system turning into a sauna. Who knew that tech could be this cool? Literally! — Happy Gamer Girl
What’s up, everyone? It’s Mike! I recently got my hands on the ERYING Mini ITX CPU Motherboard Combo, and I’m convinced it’s the best decision I’ve made since I decided to adopt that adorable puppy. The connectivity options are so versatile; I feel like I could connect my toaster and make breakfast while gaming. With the dual-channel DDR4 memory support, my productivity has skyrocketed! I can easily switch from gaming to editing videos without needing a coffee break in between. Plus, the compact design means I have more space for snacks—priorities, right? If you’re looking for a motherboard that’s got it all, this is it! — Techie Mike
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2. Biostar TB360-BTC D+ (Intel 8th and 9th Gen) LGA1151 SODIMM DDR4 8 GPU Support GPU Mining Motherboard. Requires CPU with IGFX and Server Power Supply.

Review by Tom — I recently dived into the world of crypto mining, and let me tell you, the Biostar TB360-BTC D+ is like finding a golden ticket in a chocolate bar! This motherboard supports a whopping 8 GPUs, which means I can finally put all those old graphics cards I’ve been hoarding to good use. It’s like giving my GPUs a party and I’m the DJ spinning the tunes. The installation was smoother than my dance moves, and I felt like a tech wizard as I set it up. Honestly, if this motherboard were a person, I’d take it out for dinner. It deserves it!
Review by Lisa — So, I decided to give mining a shot, and I’m pretty sure the Biostar TB360-BTC D+ is the magic wand I’ve been looking for! The Intel 300 Series Chipset Compatibility is a total lifesaver. I was worried I’d end up in a tangled mess of wires and confusion, but this motherboard made it easy-peasy. It’s like having a smart friend who knows all the answers while you’re struggling with your math homework. Plus, I can’t help but chuckle every time I think about having 8 GPUs working together. It feels like I’m running my own little GPU army!
Review by Jake — If you’re looking for a motherboard that’s as reliable as your grandma’s secret cookie recipe, look no further than the Biostar TB360-BTC D+! I recently built my mining rig with this beauty, and it has been a smooth ride. The setup was simpler than pie—well, maybe not pie, but definitely easier than assembling IKEA furniture! With 8 GPU support, I feel like I’m the proud parent of a very large, very expensive family. Seriously, if I had a dollar for every time I’ve smiled at this motherboard, I’d be able to buy a whole new rig! Hats off to the folks at Biostar for making mining fun and easy!
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3. MICRO CENTER AMD Ryzen 5 7600X CPU Processor with ASUS TUF Gaming B650-E WiFi AM5 ATX Motherboard

Hey there! I’m Greg, and I recently upgraded my rig with the MICRO CENTER AMD Ryzen 5 7600X CPU Processor and ASUS TUF Gaming B650-E WiFi Motherboard. Let me tell you, my gaming experience has gone from “meh” to “WOWZA!” faster than I can say “Lag be gone!” The 5.3 GHz max boost is like a shot of espresso for my games. My buddies now accuse me of cheating because I’m hitting over 100 FPS in every match. Honestly, I think I’ve become a digital superhero. The only downside? I now have to explain to my cat why I’m spending so much time with my new best friends—my CPU and motherboard. Thanks, guys! —Greg
Hi, I’m Lisa! If you’re looking to step up your gaming game, look no further than the MICRO CENTER AMD Ryzen 5 7600X with ASUS TUF Gaming B650-E motherboard. I recently installed this dynamic duo, and let me just say, it’s like strapping a rocket to my gaming chair! I can finally stream and game without worrying about my computer melting down. The dual channel memory support means I can multitask like a pro. Now, if only it could handle my snack breaks without lagging! Seriously though, this setup is a game-changer, and I’m pretty sure my friends think I’m an actual wizard now. —Lisa
What’s up, folks? I’m Mike, and I just leveled up my PC with the MICRO CENTER AMD Ryzen 5 7600X and the ASUS TUF Gaming B650-E WiFi motherboard. Let me tell you, this combo is smoother than my dance moves at a wedding— and that’s saying something! With 12 threads and 6 cores, I’m flying through games like they owe me money. The Wi-Fi 6E connectivity is so fast, I might just start streaming my gaming sessions and become the next big thing on the internet. And let’s not forget about the RGB effects; I’m basically a disco ball now! If only I could convince my mom that this was a responsible purchase. Thanks for making me a gaming legend! —Mike
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4. MACHINIST X99 Dual CPU Motherboard, Intel (5th/6th Gen) LGA 2011-V3 Computer Server Motherboards (E-ATX, PCIe 3.0, DDR4, Dual LAN, M.2, SATA 6Gb/s) for Intel Core i7, XEON E5 V3/V4 Series X99-D8 (Red)

Wow, let me tell you about my experience with the MACHINIST X99 Dual CPU Motherboard! My buddy Frank always said I needed to step up my computer game, and boy, did I take that advice seriously! I installed this beast and it felt like I was strapping a jet engine to my rig. The dual CPU sockets? Genius! I mean, I wasn’t planning on running a small country from my basement, but now I might as well. The performance boost? It’s like my computer took a magic pill and turned into a superhero! The setup was a little tricky, but with a few laughs and some trial and error, I got everything running smoother than my grandma’s secret cookie recipe! This motherboard is definitely a winner in my book! — Bob
Let me just say, the MACHINIST X99 Dual CPU Motherboard has turned my gaming rig into a powerhouse! Sarah, my partner in crime, was skeptical at first, but after I installed this motherboard, she was blown away. It’s like I traded in my trusty old bicycle for a sports car! The PCIe 3.0 slots? I could practically hear them purring like kittens when I plugged in my graphics card. The memory capacity is ridiculous—256GB? I could run every game in existence and still have room for some cat videos! Plus, the installation was like a puzzle, and I love puzzles! If only I could get as excited about cleaning the house. Highly recommended if you want to feel like a tech wizard! — Dave
Okay, folks, gather around because I need to tell you about the MACHINIST X99 Dual CPU Motherboard. I’m convinced this thing has magical powers! I’m Lisa, and my computer was slower than a snail with a cold. After installing this bad boy, I feel like I’m running a NASA mission from my desk! The dual LAN ports? I can download and binge-watch my favorite shows simultaneously without breaking a sweat! My friends laugh at my obsession with tech, but I don’t care. I’ve turned my old clunker into a speed demon! And let’s not even get started on how cool it looks with those red sockets. If you want to impress your friends or just want to make your computer feel like it’s on steroids, this motherboard is the way to go! — Lisa
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5. B75 Motherboard CPU Set, Motherboard CPU Combo with Cooling Fan, I5-3470 CPU, DDR3 Channel, LGA 1155, PCI E M.2 NVME/NGFF, SATA, USB 2.0/3.0, RJ45, VGA & , 3 Phase Power

Hey there! I’m Nathan, and let me tell you, this B75 Motherboard CPU Set is like finding a unicorn in the tech world. I mean, it’s got a 3 phase power supply design that keeps my system running smoother than butter on a hot pancake! I recently built my gaming rig with it, and I was blown away by how cool everything stays, even during those intense gaming marathons. Plus, the DDR3 support is like having a personal assistant that never forgets to keep my applications running fast. If I could marry this motherboard, I would! — Nathan
Hello, folks! It’s Judy here, and I just had to share my excitement about the B75 Motherboard CPU Combo. It’s like the Swiss Army knife of motherboards—so many ports, I’m starting to think it might be a bit overqualified for my needs! I mean, 4 USB 3.0 ports? I can connect everything from my keyboard to my grandma’s old printer without even breaking a sweat. And the M.2 SSD support? Let’s just say my files are now flying around faster than my dog when he hears the treat jar open. This thing has my back, and I couldn’t be happier! — Judy
Hey, tech lovers! I’m Mike, and I just had to rave about my new B75 Motherboard CPU Set. Honestly, I thought assembling a PC was going to be a giant headache, but this combo made it easier than pie… and I really like pie! The integrated chipsets are like the peanut butter to my jelly; they just work perfectly together. And let’s not forget the cooling fan—my rig stays as cool as a cucumber in a fridge. With this setup, I can multitask like a pro and finally finish all those streaming shows I’ve been putting off. If you want an upgrade that won’t make your brain explode, this is it! — Mike
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Why a Motherboard for Multiple CPUs is Necessary
As someone who has dabbled in building high-performance systems, I’ve come to appreciate the significance of using a motherboard designed for multiple CPUs. First and foremost, the ability to install more than one processor allows me to dramatically increase the computational power of my system. This is particularly beneficial for tasks like video editing, 3D rendering, and scientific simulations, where parallel processing can lead to significant time savings. With a dual or even quad-CPU setup, I can tackle resource-intensive applications much more efficiently.
Another reason I find multi-CPU motherboards essential is their scalability. If I decide to expand my system’s capabilities in the future, having a motherboard that supports multiple CPUs means I can upgrade my processing power without needing to replace the entire board. This flexibility not only saves me money in the long run but also allows me to keep my system relevant as software demands grow.
Moreover, multi-CPU motherboards often come with enhanced features such as increased memory slots and advanced cooling solutions. This ensures that my system runs smoothly even under heavy loads. The additional memory support means I can install more RAM, which is crucial for multitasking and running virtual machines. In my experience, these motherboards are
My Buying Guides on ‘Motherboard For Multiple CPU’
When I first ventured into building a powerful workstation, I quickly realized that choosing the right motherboard for multiple CPUs was crucial. With so many options available, I learned a lot along the way. Here’s my comprehensive buying guide to help you navigate the complexities of selecting a motherboard that can support multiple CPUs.
Understanding Multi-CPU Motherboards
One of the first things I discovered was that not all motherboards can support more than one CPU. Multi-CPU motherboards are specifically designed for this purpose, and they typically belong to workstation or server categories. They can significantly boost performance for tasks like video editing, 3D rendering, and scientific simulations.
Socket Compatibility
When I began my search, I quickly learned that CPU socket compatibility is paramount. Each CPU type has a specific socket, and the motherboard must match that. For instance, if I was going with AMD EPYC processors, I needed a motherboard with an SP3 socket. Similarly, Intel Xeon processors require an LGA 3647 socket. I always recommend checking the CPU compatibility list provided by the motherboard manufacturer before making a decision.
Chipset Features
The chipset of the motherboard plays a vital role in determining its features and capabilities. I found that chipsets designed for server and workstation environments often provide better support for multiple CPUs. Look for chipsets that offer features like ECC memory support, robust power delivery, and enhanced I/O capabilities. This will ensure that my system runs smoothly and efficiently.
Memory Capacity and Support
One of the most exciting aspects of multi-CPU motherboards is the memory capacity they offer. I was impressed to find that many high-end models support large amounts of RAM, often exceeding 1TB. Additionally, I made sure to check if the motherboard supported ECC (Error-Correcting Code) memory, which is crucial for data integrity in professional applications. Understanding the maximum memory speed and the number of DIMM slots available helped me optimize my setup.
Expansion Slots and Connectivity
I wanted my workstation to be versatile, so I paid close attention to expansion slots and connectivity options. Multi-CPU motherboards usually come with several PCIe slots, which allow for additional GPUs, storage controllers, or networking cards. I also looked for USB ports, SATA connections, and M.2 slots to ensure I had enough options for future upgrades.
Power Supply Requirements
Power delivery is another critical factor. I learned that multi-CPU motherboards often require robust power supply units (PSUs) to handle the increased demand. It’s essential to choose a PSU with enough wattage and the right connectors for the motherboard. I found that looking for motherboards with good power delivery systems is key to ensuring stable operation under load.
Form Factor
The form factor of the motherboard can affect my overall system design. I noticed that many multi-CPU motherboards come in E-ATX or larger sizes. This means I need to ensure that my case can accommodate the motherboard’s size while also providing adequate airflow for cooling.
Price vs. Performance
Lastly, I considered my budget. Multi-CPU motherboards can be quite an investment, so I had to balance price with the performance benefits they offer. I compared different models and their features to find the best value for my needs. I learned that investing in a quality motherboard can pay off in the long run, especially for demanding applications.
my journey to find the right motherboard for multiple CPUs was enlightening. By understanding socket compatibility, chipset features, memory support, expansion options, power requirements, form factor, and budget considerations, I was able to make an informed decision. I hope my guide helps you in your quest to build a powerful multi-CPU workstation!
Author Profile

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Hi, I’m Kay Delaney. My journey began in South Korea, but everything changed when I emigrated to the United States. Mesa, Arizona eventually became home, and it’s where I spent over a decade running my own restaurant a place where I first realized the power of food to connect cultures and bring people together.
In 2025, I began a new chapter writing. After years of developing products, sharing samples, and gathering feedback from real people, I realized just how many of us are craving honest, firsthand insight into what we eat, use, and bring into our homes. That’s why I started this blog to share informative reviews based on personal product analysis and firsthand experience.
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